RESEARCH

 

Overview

Dr. Kuhn’s research integrates neuroimaging, neuropsychological assessment and neuromodulation to investigate functional neuroanatomy - that is, what brain networks and brain functions give rise to each aspect of cognition, emotion, and behavior. This is also called the brain-behavior relationship. Neuroimaging allows the brain’s structure, activity, and connectivity to be viewed, directly measured and quantified. Neuropsychological assessment allows for cognition (e.g. attention, memory, problem solving), emotion (e.g. anxiety, depression), and behavior (e.g. motor skills, real world function) to be quantified. Brain and neuropsychological changes caused by healthy development, healthy aging, neurologic and psychiatric diseases are used to test theories about the brain-behavior relationship. Neuromodulation, such as with focused ultrasound or transcranial magnetic or electrical stimulation, also allows for specific regions of the brain to be changed. Then, neuroimaging and neuropsychological assessment can assess how those changes affect the structure and function of the brain, cognition, emotion and behavior. In this way, Dr. Kuhn’s research seeks to further our understanding of the brain-behavior relationships and help develop and validate clinical tools for improving cognition and emotion across a host of neurological and psychiatric conditions.

 

Publications

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2020, All Articles Taylor Kuhn 2020, All Articles Taylor Kuhn

Treatment of dementia with bosutinib: An open-label study of a tyrosine kinase inhibitor

Kennedy D. Mahdavi, Sheldon E. Jordan, Hannah R. Barrows, Maša Pravdic, Barshen Habelhah, Natalie E. Nicodemus, Robin B. Blades, Jessica J. Iovine, Sergio A. Becerra, Rachel A. Steiner, Marisa Chang, Santosh Kesari, Alexander Bystritsky, Ed O'Connor, Hyman Gross, F. Scott Pereles, Mike Whitney, Taylor Kuhn. (2020). Neurology.

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2019, All Articles Taylor Kuhn 2019, All Articles Taylor Kuhn

Effects of Diffusion MRI Model and Harmonization on the Consistency of Findings in an International Multi-cohort HIV Neuroimaging Study.

Nir, T. M., Lam, H. Y., Ananworanich, J., Boban, J., Brew, B. J., Cysique, L., Fouche, J. P., Kuhn, T., Porges, E. S., Law, M., Paul, R. H., Thames, A., Woods, A. J., Valcour, V. G., Thompson, P. M., Cohen, R. A., Stein, D. J., & Jahanshad, N. (2019). Computational Diffusion MRI .

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