Interactive Curriculum Vitae
APRIL 2023
Dr. Kuhn and his UCLA lab publish the first-in-person use of low intensity, transcranial focused ultrasound (tFUS) targeting the amygdala and the entorhinal cortex. This represents the first time tFUS has been used in people to modulate blood flow and connectivity of these brain regions important for emotion regulation and anxiety (amygdala) as well as learning and memory (entorhinal cortex). The Kuhnlab is continuing to build on this work by investigating tFUS of the amygdala for improving anxiety, tFUS of the entorhinal cortex for improving learning and memory in Alzheimer's disease, as well as in other parts of the brain in attempts to improve symptoms in Parkinson's disease as well as anhedonic depression.
February 2023
Dr. Kuhn Chairs symposium on focused ultrasound neuromodulation at the 5th International Brain Stimulation Conference in Lisbon, Portugal
October 2022
Kuhnlab website and social media launch with kuhnlab.io
september 2022
UCLA and Dr. Kuhn officially launch dedicated tFUS research website: https://uclastaglin.wixsite.com/staglinccn
september 2022
Dr. Kuhn founds and chairs the new ENIGMA Neuromodulation Working Group. Co-chaired by experts in deep brain stimulation, transcranial magnetic stimulation, transcranial electrical stimulation, peripheral nerve stimulation and artificial intelligence, the ENIGMA-Neuromod Working Group is an international initiative seeking to further neuromodulation research, develop novel neuromodulatory clinical uses and generate cartographies of the brain. https://enigma.ini.usc.edu/ongoing/enigma-neuromodulation/
July 2022
UCLA undergraduate Nolan Dang wins UCLA Deans Award at the Undergraduate Research and Creativity Showcase, a part of Undergraduate Research Week 2022. Nolan was awarded for his research “Modulating Symptoms of Anxiety with Transcranial Focused Ultrasound: Decreased Psycho-physiological Responses Associated with Non-invasive Deep Brain Neuromodulation” conducted in the Kuhn Lab.
June 2022
Dr. Kuhn discusses the future of transcranial focused ultrasound, neuromodulation, health, wellness and neuro-ethics on Curiosity Stream's Suppressed Science show: https://curiositystream.com/video/5255
April 2022
Dr. Kuhn announces research effort into digital therapeutics with world-renowned artist and longtime collaborator Refik Anadol: link to annoucement
April 2022
Dr. Kuhn lectures on the current state-of-the-science of transcranial focused ultrasound neuromodulation: https://vimeo.com/698832935
November 2021
Dr. Kuhn completes the process to become a Board Certified Clinical Neuropsychologist through the American Board of Professional Psychology and the American Board of Clinical Neuropsychology (ABPP/CN).
SEPTEMBER 2021
Dr. Kuhn and UCLA colleagues publish two papers on the safety of transcranial focused ultrasound for use in human brains:
Stern, J. M., Spivak, N. M., Becerra, S., Kuhn, T. P., Korb, A. S., Kronemyer, D., ... & Bystritsky, A. (2021). Safety of focused ultrasound neuromodulation in humans with temporal lobe epilepsy. Brain Stimulation.
Spivak NM, Korb AS, Reyes SD, Bych BP, Schafer SF, Khanlou N, Johnson EA, Schafer ME, Cohen MS, Kuhn T, & Bystritsky A. Histological Examination of Transcranial Focused Ultrasound Effects on Human Brain Tissue. Brain Stimulation. 2021; 14(6):1486-8. DOI: 10.1016/j.brs.2021.09.015. PubMed PMID: 34607066
SEPtember 2021
Dr. Kuhn and colleagues publish a case report demonstrating the treatment of COVID-related cognitive difficulties with MRI-guided near infrared laser: Haroon, J., Mahdavi, K., Zielinski, M. A., Habelhah, B., Chan, L., Bystritsky, A., ... Kuhn, T., Jordan, S. (2021). A case of COVID-encephalopathy imaged with fMRI and treated with near infrared light. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation.
2021
Dr. Kuhn and colleagues publish review paper positing the brain networks underlying a cutting edge model of anxiety disorders with an aim towards directing the development of future treatments for psychiatric disorders: Bystritsky, A., Spivak, N.M., Dang, B.H., Becerra, S.A., Distler, M.G., Jordan, S.E., & Kuhn, T.P. (2021). Brain Circuitry Underlying the ABC Model of Anxiety. Journal of Psychiatric Research.
2021
The ENIGMA-HIV consortium publishes in JAMA: Nir, T. M., Fouche, J. P., Ananworanich, J., Ances, B. M., Boban, J., Brew, B. J., … & Jahanshad, N. (2021). Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV. JAMA network open, 4(1), e2031190-e2031190.
MARCH 2021
Dr. Kuhn and Dr. Margaret Distler receive private donor support to initiate a first of its kind multisite clinical trial, in partnership with Harvard University and Medical University of South Carolina, to pilot transcranial focused ultrasound for the treatment of generalized anxiety disorder.
January 2021
Dr. Kuhn and his colleagues Drs. Lev Gottlieb (UCLA), Joseph Gullett (UF), Andrew Bismark (UCDD) and Pamela Douglas (UCF/UCLA) join as Editors to launch a Frontiers in Digital Health, Special Topic: Quantified Self and Machine Learning Assessment and Prediction of Brain-based Health.
AUGUST 2020
Dr. Kuhn and Dr. Bookheimer receive additional support for their investigation of transcranial focused ultrasound for Alzheimer’ disease from a private donor.
JULY 2020
Dr. Kuhn and Dr. Bookheimer receive grant support from the UCLA Clinical & Translational Science Institute to pilot transcranial focused ultrasound in Parkinson’s disease.
June 2020
Połczyńska M.M., Monti, M., Kuhn T., Wang, H., Ly, T., Japardi K., Shattuck, D., Anderson, A., Curtiss, S., Dronkers, N., Benjamin C., Bookheimer S.Y. Optimizing grammar tasks for pre-operative fMRI based on task-based and resting-state activation. Organization for Human Brain Mapping annual meeting 2020, Montreal, Canada.
September 2019
Dr. Kuhn collaborates with Flow Research Collective on a CBD and Flow State project involving professional surfers.
August 2019
Dr. Kuhn joins as an instructor for the UCLA Functional Neuroanatomy course.
August 2019
Dr. Kuhn joins the Executive Board for the UCLA Staglin Center for Cognitive Neurosciences.
JUNE 2016
Dr. Kuhn and his Neuropsychology, Neuroimaging and Neuromodulation [KT3] laboratory are the first to use low intensity transcranial focused ultrasound to modulate brain activity of the entorhinal cortex (memory center) and amygdala (emotion center) in humans.
APRIL 2019
Dr. Kuhn and Dr. Susan Bookheimer receive grant funding from the Alzheimer’s Association to pilot transcranial focused ultrasound as a non-invasive neuromodulation therapy for Alzheimer’ disease and its prodrome, amnestic MCI.
2018
Dr. Kuhn and an international team use machine learning to predict people’s age using only brain MRI data and, extending his earlier work, show that HIV infection augments the aging process by accelerating the predicted age of brains with HIV (Kuhn, T., Kaufmann, T., Doan, N.T., Westlye, L.T., Jones, J., Nunez, R.A., Bookheimer, S.Y., Singer, E.J., Hinkin, C.H., Thames, A.D. (2018). An Augmented Aging Process in Brain White Matter in HIV. Human Brain Mapping. 39(6), 2532-2540.
September 2018
Dr. Kuhn becomes an attending psychologist for the LA chapter of the Physicians for Human Rights movement, Los Angeles Human Rights Initiative.
July 2018
Dr. Kuhn starts a training program for psychology interns and postdoctoral fellows to learn to provide services to people seeking asylum and special immigrant juvenile status through the LA Human Rights Initiative.
2017
Neurolinguist Monika Połczyńska and Dr. Kuhn further their collaboration by improving the use of fMRI to assist with localizing language prior to brain surgeries involving brain tissue near areas in charge of language functions in individual patients: Połczyńska M., Japardi K., Curtiss S., Moody, T., Benjamin C., Cho A., Vigil C., Kuhn T., Jones M., Bookheimer S. (2017). Improving language mapping in clinical fMRI through assessment of grammar. Neuroimage: Clinical.
2017
Dr. Kuhn publishes the results of a clinical trial following patients successfully cured of Hepatitis C as relates to changes in their brains and cognitive performance after clearing the virus (Kuhn, T.P., Sayegh, P., Jones, J.D., Smith, J., Sarma, M.K., Ragin, A., Singer, E.J., Thomas, A., Thames, A.D., Castellon, S.A., Hinkin C.H. (2017). Improvements in Brain and Behavior Following Eradication of Hepatitis C. Journal of Neurovirology, 23(4), 593-602.
2017
Dr. Kuhn takes over as the lead as the project coordinator for the Mapping the Human Connectome Project in Typical Development (Human Connectome Project – Development).
2017
Neurolinguist Monika Połczyńska and Dr. Kuhn work together to validate language tasks to improve the localization of language in the brain prior to brain surgery with the ultimate goal of protecting patients and improving outcomes post-surgery: Połczyńska, M., Kuhn, T., You, S. C., Walshaw, P., Curtiss, S., & Bookheimer, S. (2017). Assessment of grammar optimizes language tasks for the intracarotid amobarbital procedure. Epilepsy & Behavior, 76, 89-100.
2016
Dr. Kuhn contributes to the scientific debate about aging in the context of HIV infection, using advanced MRI techniques to demonstrate that aging and HIV synergistically effect the shape of subcortical brain structures (Kuhn, T.,Schonfeld, D., Sayegh, P., Jones, J.D., Arentoft, A., Hinkin, C.H., Bookheimer, S.Y., & Thames, A.D. (2016). The Effects of HIV and Aging on Subcortical Shape Alterations: A 3D Morphometric Study. Human Brain Mapping. DOI 10.1002/hbm.23436.
2016
Dr. Kuhn brings UCLA into the Enhancing Neuroimaging Genetics through Meta-Analysis HIV (ENIGMA-HIV) consortium.
2016
Dr. Kuhn takes the lead as the project coordinator for the Mapping the Human Connectome Project in Typical Aging (Human Connectome Project – Aging) – Inception of project.
September 2016
Dr. Kuhn joins as course instructor for the UCLA Neuropsychology Informal Brown Bag Lecture Series.
July 2016
Dr. Kuhn receives a subgrant from the NIMH R25 to support his individual research and training in NeuroAIDS Disparities through a Mt. Sinai Institute summer training program. Project title: Accelerated Brain and Cognitive Aging in HIV-Positive African and European Americans.
2015
Dr. Kuhn publishes a methods paper extending the reliability of diffusion tensor imaging for research use (Kuhn, T.,Gullett, J. M., Boutzoukas, A. E., Ford, A., Nguyen, P., Colon-Perez, L. M., Triplett, W., Price, C. C., Mareci, T. H., Bauer, R. M. (2015). Test-Retest Reliability of High Angular Resolution Diffusion Imaging (HARDI) Acquisition Assessed via TBSS, Tractography and a Novel Graph Theory Metric. Brain Imaging and Behavior.
June 2015
Dr. Kuhn receives a UCLA scholarship “Exploring the Human Connectome” to train in the HCP data analytic methods in preparation for his upcoming transition to project coordinator for the Lifespan Human Connectome Projects.
FEBRUARY 2015
Dr. Kuhn receives the Phillip M. Rennick Research Award from the International Neuropsychological Society.
September 2014
Dr. Kuhn accepts a NIH T32 Training Grant, Neuropsychology HIV/AIDS Fellowship (MH19535), through which he will complete his Postdoctoral Fellowship at UCLA.
JUNE 2014
Dr. Kuhn is the recipient of the Greiffenstein-Kaplan Research Award from the American Academy of Clinical Neuropsychology.
Non-UCLA News
August 2022
Dr. Kuhn joins the board of Lumena Labs.
may 2022
Architex receives funding from two Cardano Project Catalyst Fund8 proposal. Proposal 1 seeks to integrated Architex with Pathform, a mission offering microinterventions for conscious wellness which will be individually tailored to users based on their Architex-dervied cognitive type. Proposal 2 seeks to use the Architex-based cognitive profile as a static user ID for access and authentication in web2 and web3 applications. In tandem with this static user ID, biometric-based dynamic ID and authentication will be developed which together will make up a user’s NeuralPrint: an authentication technology based on user’s unique cognitive profile (Architex) as well as dynamic neural and biometric signatures.
April 2021
Dr. Kuhn joins the Pacific Neuroscience Institute as a clinical research consultant.
June 2020
Dr. Kuhn joins as a consultant for Wonder Sciences.
January 2020
Dr. Kuhn and Dr. Gottlieb launch Scientia.
January 2020
Dr. Kuhn joins the Board of the Pacific Institute for Medical Research.
July 2019
Dr. Kuhn and Dr. Gottlieb launch Integrated Clinic.
June 2017
Dr. Kuhn joins as a consultant for the Synaptec Consortium.
June 2017
Dr. Kuhn and Dr. Gottlieb launch Architex.
Art Collaborations
October 2021
Dr. Kuhn’s collaboration with Refik Anadol Studios highlighted at 72nd Annual Astronautical Congress in Dubai.
july 2021
Refik Anadol Studio and Dr. Kuhn art collaboration wins Brain Art award at 2021 Organization for Human Brain Mapping (OHBM) Conference. This art was also highlighted in a published paper on the OHBM Brain Art symposium: https://psyarxiv.com/uywc5/
april 2021
Dr. Kuhn discusses Neuroscience, AI, and Art with Refik Anadol for Nvidia GTC Conference: https://www.nvidia.com/en-us/on-demand/session/gtcspring21-art3339/
february 2021
NVIDIA sponsor the Biennale Art Exhibition.
december 2020
Refik Anadol Studios and Dr. Kuhn collaboration accepted as a main exhibit for the 2021 Venice Biennale Art and Architecture Exhibition, opening in May 2021.
November 2020
Dr. Kuhn and his lab partner with world-renowned technology-driven artist Refik Anadol and his digital arts studio (Refik Anadol Studio) to develop a professional art-science collaboration. Together Refik Anadol Studio and Dr. Kuhn’s lab are training machine learning algorithms multimodal neuroscience data (e.g. human brain MRIs). The results are free-form machine imaginings of human structural and functional neural networks. This collaboration has yielded multiple scientific manuscripts (in preparation) and numerous art projects, the first of which was accepted as a primary installation at the 2021 Venice Biennale, 17th International Art & Architecture Exhibition: “How We Live Together.” The visual outcome for the Venice Biennale is a 3D-printed architectural structure of machine imagined tractography with shifting functional networks projection mapped onto and through the structure, allowing visitors to wander through a brain simulation architected by a self-driven machine that speculates a new sense of space.
February 2019
Dr. Kuhn partners with artist Michael Bermudez, whose work lies at the intersection of art, math, music, science and chaos, to create an interactive painting based on tractography of Dr. Kuhn’s brain.